27 January
Medicines and Healthcare Products Regulatory Agency (MHRA) gives permission for human trials by Parexel of antibody drug TGN1412, created by German pharmaceutical company TeGenero.

22 February
Volunteers selected for trial

13 March
TGN1412 administered in trials at Northwick Park Hospital, London. The six men's immune systems react to drug with 'cytokine storm', resulting in agonising, life-threatening injuries. One volunteer, Nino Abdel Hady, was described as looking like 'the Elephant Man' by his tearful girlfriend, Myfanwy Marshall, because his head was so swollen.

5 April
Interim report finds no evidence of human error, contamination or failure to follow protocols.

27 April
Six men receive interim payouts of £10,000 each.

25 May
MHRA inquiry finds 'unexpected biological effect' most likely cause of incident.

27 June
Ryan Wilson, the most seriously injured victim - who spent three weeks in a coma with heart, kidney and liver failure, pneumonia and septicaemia - leaves hospital.

19 July
Mr Wilson returns to hospital to have toes amputated.

August
David Oakley is told that he has the early indications of a lymphoid malignancy, an aggressive and life-threatening form of cancer. Mr Oakley has also suffered memory problems and has undergone neurological tests to find out if there has been permanent damage to his brain.

7 December
The government inquiry group, appointed by the Health Secretary, Patricia Hewitt, and led by scientist Professor Gordon Duff, makes 22 recommendations about avoiding another drug trial disaster. It does not identify who was at fault.