Blue notes

When you're down, drink and drugs offer an easy way out. But the bill for escapism always arrives the next day, says Nick Johnstone.

A time for treatment

Leader: The biggest challenge facing the mentally ill is the lack of access to urgently needed treatment.

Doctor’s notes

A row has broken out over a new, cheaper version of a schizophrenia drug. But why, if it saves the NHS money?

Nip and tuck and nip again

Hope Donahue was a beautiful, wealthy teenager, fixated by her appearance. By 23, she was a veteran of cosmetic surgery. Perfect nose, lips, cheeks seemed to spell happiness. She tells how she finally realised she had to escape the scalpel.

Linford Rees

Psychiatrist who contributed to the development of effective drug therapy.

Trapped in gender limbo

Fifteen years ago, Paul Rowe felt driven to physically change gender after a series of personal traumas. But, as he tells David Batty, his hopes of a happier life have not come true.

Q&A: transsexualism

There are around 2,000 transsexuals in the UK. David Batty explains what a gender change involves and what rules govern treatment.